Heritable Human Genome Editing (2020)
Chapter: Appendix D: Acronyms and Abbreviations
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Suggested Citation:
"Appendix D: Acronyms and Abbreviations." National Academy of Medicine, National Academy of Sciences, and the Royal Society. 2020. Heritable Human Genome Editing. Washington, DC: The National Academies Press.
doi: 10.17226/25665.
D
Acronyms and Abbreviations
| AG-haESCs | Androgenetic haploid embryonic stem cells |
| AIDS | Acquired immune deficiency syndrome |
| ARRIGE | Association for Responsible Research and Innovation in Genome Editing |
| ART | Assisted reproductive technology |
| CAR-T cells | Chimeric antigen receptor T cells |
| Cas | CRISPR associated protein |
| Cas9 | CRISPR associated protein 9 |
| CF | Cystic Fibrosis |
| CRISPR | Clustered regularly-interspaced short palindromic repeats |
| DNA | Deoxyribonucleic acid |
| ES cell | Embryonic stem cell |
| ESHRE | European Society of Human Reproduction and Embryology |
| FDA | Food and Drug Administration |
| FH | Familial Hypercholesterolemia |
| gRNA | Guide ribonucleic acid |
| HDR | Homology-directed repair |
| HFEA | Human Fertilisation and Embryology Authority |
Suggested Citation:
"Appendix D: Acronyms and Abbreviations." National Academy of Medicine, National Academy of Sciences, and the Royal Society. 2020. Heritable Human Genome Editing. Washington, DC: The National Academies Press.
doi: 10.17226/25665.
| HHGE | Heritable human genome editing |
| HIV | Human immunodeficiency syndrome |
| hPGCLC | Human primordial germ-like cell |
| HSC | Hematopoietic stem cell |
| ICH | International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use |
| ICM | Inner cell mass |
| ICSI | Intracytoplasmic sperm injection |
| IFFS | International Federation of Fertility Societies |
| IOB | International Oversight Board |
| iPSC | Induced pluripotent stem cell |
| ISAP | International Scientific Advisory Panel |
| IVF | In vitro fertilization |
| IVG | In vitro gametogenesis |
| LDL | Low-density lipoprotein |
| MII | Metaphase II |
| MRT | Mitochondrial replacement techniques |
| MST | Maternal spindle transfer |
| mtDNA | Mitochondrial DNA |
| NGS | Next-generation sequencing |
| NHEJ | Non-homologous end joining |
| ntESC | Nuclear transfer embryonic stem cell |
| OHSS | Ovarian hyperstimulation syndrome |
| PAM | Protospacer-adjacent motif |
| PB | Polar body |
| PCR | Polymerase chain reaction |
| PGC | Primordial germ cell |
| PGCLC | Primordial germ cell-like cell |
| PGT | Preimplantation genetic testing |
| PNT | Pronuclear transfer |
| RNA | Ribonucleic acid |
| SART | Society for Assisted Reproductive Technology |
| SCD | Sickle cell disease |
| SNP | Single nucleotide polymorphism |
Suggested Citation:
"Appendix D: Acronyms and Abbreviations." National Academy of Medicine, National Academy of Sciences, and the Royal Society. 2020. Heritable Human Genome Editing. Washington, DC: The National Academies Press.
doi: 10.17226/25665.
| SNV | Single nucleotide variant |
| SSC | Spermatogonial stem cell |
| TALEN | Transcription activator–like effector nuclease |
| WGS | Whole-genome sequencing |
| WHO | World Health Organization |
| ZFN | Zinc-finger nuclease |
Suggested Citation:
"Appendix D: Acronyms and Abbreviations." National Academy of Medicine, National Academy of Sciences, and the Royal Society. 2020. Heritable Human Genome Editing. Washington, DC: The National Academies Press.
doi: 10.17226/25665.
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