The NRC will appoint an ad hoc committee to conduct the quadrennial review of the National Nanotechnology Initiative (NNI). The overall objective of this review is to make recommendations to the Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the White House National Science and Technology Council and to the National Nanotechnology Coordination Office that will improve the value of the NNI’s research and development (R&D) strategy and portfolio to the economic prosperity and national security of the United States. Toward this objective, this quadrennial NNI review will include the following tasks: