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State of Molybdenum-99 Production and Utilization and Progress toward Eliminating Use of Highly Enriched Uranium

Completed

The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world’s supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. This report examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

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