An ad hoc planning committee will organize and conduct a public workshop to examine how the implementation of novel technology in health care and lessons from prior adoptions can be applied to genomic medicine advances. A variety of examples in health care may be considered, including the adoption of electronic health records or the introduction of imaging and other technologies. The workshop goal will be to learn from existing examples and examine the challenges, opportunities, and best practices to implementing genomic technologies in the health care system without exacerbating health care disparities. A diverse stakeholder group, which may be comprised of health care system leadership, clinical providers, patients, implementation science experts, and others, will be invited to present their experiences and perspectives. The planning committee will develop the workshop agenda, select speakers and discussants, and moderate the discussions. A summary of the workshop will be prepared by a designated rapporteur in accordance with institutional policy and procedures.