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Roundtable/Forum

Roundtable on Genomics and Precision Health

The Roundtable on Genomics and Precision Health brings together voices in the field to encourage innovation and actions that foster the wide adoption of and access to the benefits of genomics and precision health. Our vision is to realize the full potential of health for all through genomics and precision health. Our current work focuses on driving innovation, spurring adoption, driving access, and shaping the policy dialogue about genomics and precision health.

In progress

Any project, supported or not by a committee, that is currently being worked on or is considered active, and will have an end date.

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"We catalyze innovation and actions that foster the wide adoption of and access to genomics and precision health."

Core Themes
Innovation: New Technologies, Tools, and Therapeutics

Innovative approaches can accelerate the commercialization and integration of genomics-based diagnostics, tools, and therapies. The roundtable explores barriers and facilitators of innovation, lessons learned from successful innovation efforts, and ways to ensure new technologies for participants and patients.
 

Past Work:

•  Exploring Applications of AI in Genomics and Precision Health: A Workshop

•  Next-Generation Screening - The Promise and Perils of DNA Sequencing of Newborns at Birth: A Workshop

•  Direct to Consumer Genetic Testing: What are the Policy Issues that Society Must Address? A Workshop 

•  Innovations in Service Delivery in the Age of Genomics: A Workshop

•  Diffusion and Use of Genomic Innovations in Health and Medicine: A Workshop

•  DIGITizE: Displaying and Integrating Genetic Information Through the EHR Action Collaborative

•  Establishing Precompetitive Collaborations to Stimulate Genomics Driven Drug Development: A Workshop

•  New Paradigms in Drug Discovery: How Genomic Data Are Being Used to Revolutionize the Drug Discovery and Development Process - A Workshop

•  Barriers to the Development and Utilization of Genome-Based Diagnostic Technologies: A Workshop

•  The Role of Digital Health Technologies in Drug Development: A Workshop

•  Exploring the Current Landscape of Consumer Genomics: A Workshop

•  Sharing Clinical Trial Data: Reflecting Back and Looking Ahead - A Workshop

•  Deriving Drug Discovery Value from Large-Scale Genetic Bioresources: A Workshop

•  Conflict of Interest in Medical Innovation: Assuring Integrity while Facilitating Innovation in Medical Research: A Workshop

•  Refining Process for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests: A Workshop

•  Genomics-Enabled Drug Repurposing and Repositioning: A Workshop

•  Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development: A Workshop

•  Sharing Clinical Research Data - A Workshop

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Dialogue

Through a variety of activities, collaborations, and engaging new voices, the roundtable shares their work and outputs to inform and advance the field of genomics and precision health.
 

Past Work:

•  The Value of Genetic and Genomic Technologies: A Workshop

•  The National Academies’ Roundtable on Genomics and Precision Health: Where we have been and where we are heading*

•  Event - Views & Voices: Reporting Genetics and Genomics

•  Event- Strategic Plan Reflection on the Roundtable's Work since 2020

•  ASHG Ancillary Event: Realizing the Full Potential of Health for All Through Genomics and Precision Health: A discussion with the National Academies Genomics Roundtable 

•  National Society of Genetic Counselors Webinar: Realizing the Full Potential of Health for All Through Genomics and Precision Health - A discussion with the National Academies Genomics Roundtable.

•  Genetically Speaking Mini-Series: The Future of Genomics and Precision Health - Roundtable members were invited to participate in this external activity.

*Disclaimer: This article is not produced by the National Academies of Sciences, Engineering, and Medicine and may not represent the views of the institution.

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Adoption & Implementation

Despite advances in genomics, integrating genomics data in clinical care has been challenging. The roundtable highlights evidence-based practices across health care and public health for bridging the gap from genomics research to the implementation of and access to genomics and precision health in clinical care.

Past Work:

• 
Examining Clinical Guidelines for the Adoption of Genomics Testing: A Workshop

•  Sustaining Community Engagement in Genomics Research: A Workshop

•  Improving Diversity of the Genomics Workforce: A Workshop

•  Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health: A Workshop

•  Evidence Generation for Genomic Diagnostic Test Development: A Workshop

•  Ethical, Legal, Social, and Policy Issues Related to the Access to, Use and Storage of Newborn Screening Samples: A Workshop 

•  Genomics and Population Health Action Collaborative

•  Bioinformatics and Clinical Genomics - Integrating Industrial Scale Genomic Information into Clinical Practice: A Workshop

•  Applying an Implementation Science Approach to Genomic Medicine: A Workshop

•  Improving Genetics Education in Graduate and Continuing Health Professional Education: A Workshop

•  Genomics-Enabled Learning Health Care Systems: Gathering and Using Genomic Information to Improve Patient Care and Research - A Workshop

•  Assessing Genomic Sequencing Information for Health Care Decision Making: A Workshop

•  Improving the Efficiency and Effectiveness of Genomic Science Translation: A Workshop 

•  Evidence for Clinical Utility of Molecular Diagnostics in Oncology: A Workshop

•  Assessing the Economics of Genomic Medicine: A Workshop

•  Implementing and Evaluating Genomic Screening Programs in Health Care Systems: A Workshop

•  Understanding Disparities in Access to Genomic Medicine: A Workshop

•  Improving racial diversity in the genomics workforce: An examination of challenges and opportunities*

 

*Disclaimer: This article is not produced by the National Academies of Sciences, Engineering, and Medicine and may not represent the views of the institution.

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Our mission

The work of this roundtable engages a variety of interested parties to encourage innovation, spur adoption and implementation, and shape dialogue in genomics and precision health. Roundtable activities, including public workshops, membership meetings, Action Collaboratives, and other information-gathering activities, provide opportunities for discussing pressing challenges and developments in the field to highlight potential solutions, encourage collaboration, and identify areas for action.

Influential Leadership

The roundtable membership includes leaders from government, academia, pharmaceutical and biotechnology companies, professional groups and associations, health systems, and patient-focused organizations. Roundtable members work together to illuminate critical issues in the field and explore opportunities for driving innovation, spurring adoption and access, and shaping the policy dialogue on genomics and precision health. View members.

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Process

Roundtables create communal environments to foster dialogue across sectors and institutions. Although roundtables do not produce solutions themselves, they illuminate issues that need to be resolved, and opportunities for further work are often developed from meetings, workshops, and publications. For example, the activities of a roundtable may result in the establishment of a separate consensus study committee. Unlike a consensus study committee, which publishes a report with conclusions and recommendations, a roundtable may not issue work with such advice.

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Work with Us

The roundtable brings together leaders from government, academia, industry, foundations, associations, patient communities, and health systems, and in doing so serves to drive innovation, spur adoption and access, and shape the policy dialogue on genomics and precision health.

Contact Sarah Beachy:

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Description

The Roundtable on Genomics and Precision Health (previously called the Roundtable on Translating Genomic-Based Research for Health) brings together leaders from government, academia, industry, foundations, associations, patient communities, and other stakeholder groups to meet and discuss global issues surrounding the translation of genomics and genetics research findings into medicine, public health, education, and policy. The primary purpose of the Roundtable is to foster dialogue across sectors and among interested parties and institutions, and to illuminate and scrutinize critical scientific and policy issues where Roundtable engagement and input will help further the field.

The Roundtable membership identifies scientific and policy issues where discussion and collaboration will help enable the translation of genomics into health care applications. Specific issues and agenda topics are determined by the Roundtable members, and span a broad range of issues relevant to the translation process. Current areas of emphasis include the development of targeted therapeutics and diagnostics, clinical implementation of genomic medicine, health IT and mhealth, the use of genomic information for health care decision making, next generation sequencing, using genomic information and data science to generate knowledge for clinical practice and research, and education and ethical, legal, and social issues.

To achieve its objectives, the Roundtable conducts structured discussions, public workshops, and symposia and enters into information-gathering activities, develops authored perspectives, organizes collaboratives, and publishes workshop summaries.

Collaborators

Committee

Robert L. Nussbaum

Co-Chair

Catherine A. Wicklund

Co-Chair

Devin Absher

Ex Officio Member

Aris Baras

Ex Officio Member

James Beck

Ex Officio Member

Natasha Bonhomme

Ex Officio Member

Colleen Caleshu

Ex Officio Member

Christina Daulton

Ex Officio Member

Aaron Goldenberg

Ex Officio Member

Jennifer Goldsack

Ex Officio Member

Richard J. Hodes

Ex Officio Member

Adriana Huertas-Vazquez

Ex Officio Member

Jessica Hurt

Ex Officio Member

Mira Irons

Ex Officio Member

Jennie Jarrett

Ex Officio Member

Katherine Johansen Taber

Ex Officio Member

Sarah Kalia

Ex Officio Member

Alisha S. Keehn

Ex Officio Member

Muin J. Khoury

Ex Officio Member

Bruce Korf

Ex Officio Member

Charles Lee

Ex Officio Member

Debra G. Leonard

Ex Officio Member

Toby Lowe

Ex Officio Member

Christa Martin

Ex Officio Member

Jennifer Moser

Ex Officio Member

Kenneth Offit

Ex Officio Member

Amanda Perl

Ex Officio Member

Jonathan Pevsner

Ex Officio Member

Kathryn A. Phillips

Ex Officio Member

Victoria M. Pratt

Ex Officio Member

Sheri Schully

Ex Officio Member

Anil Shanker

Ex Officio Member

Angela Starkweather

Ex Officio Member

Sharon Terry

Ex Officio Member

Joyce Tung

Ex Officio Member

Karen Weck

Ex Officio Member

Michelle Ann Penny

Member

Jacquelyn Y. Taylor

Member

Sarah Wordsworth

Member

Sponsors

23andMe

All of Us Research Program

American Academy of Nursing

American College of Medical Genetics and Genomics

American Medical Association

American Society of Clinical Oncology

American Society of Human Genetics

Association for Molecular Pathology

Biogen

College of American Pathologists

Geisinger Health

Genome Medical

Health Resources and Services Administration

Illumina Inc.

Kaiser Permanente

Myriad Genetics

National Cancer Institute

National Human Genome Research Institute

National Institute of Mental Health

National Institute of Nursing Research

National Institute on Aging

National Society of Genetic Counselors, Inc

The Jackson Laboratory (JAX)

University of California, San Francisco

University of Vermont Health Network Medical Group

Staff

Sarah Beachy

Lead

Michelle Drewry

Ashley Pitt

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