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Advancing Disease Modeling Techniques in Animal-based Research in Support of Precision Medicine: A Workshop

Completed

Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. This workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine.

Description

An ad hoc planning committee will plan and conduct a public workshop to explore the potential of ongoing and future research in animal models with implications for precision medicine. This workshop will bring together experts on the use of state-of-the art technologies and technological advances to explore

· How the design, creation, and analysis of current and next-generation animal models can inform the practice of precision medicine

· Reproducibility concepts to improve the clinical relevance of animal-based validation experiments and pre-and co-clinical trials in the context of precision medicine

· Welfare and regulatory considerations of current and especially next-generation animal models that would inform the design of targeted, personalized therapies.

The planning committee will develop the workshop agenda, select and invite speakers and discussants, and moderate the discussions. An individually-authored proceeding of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Sponsors

American Veterinary Medical Association

Baylor College of Medicine

Emory University

Genentech

GlaxoSmithKline

Johnson & Johnson

Massachusetts General Hospital

Medical College of Wisconsin

Merck & Co., Inc.

National Institutes of Health

National Primate Research Centers

National Science Foundation

Novartis Institutes for BioMedical Research

University of California, Davis

University of Miami

University of Michigan

University of Pittsburgh

Yale University

Staff

Lida Anestidou

Lead

Major units and sub-units

Division on Earth and Life Studies

Lead

Institute for Laboratory Animal Research

Lead

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