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Adult Attention-Deficit/Hyperactivity Disorder: Diagnosis, Treatment, and Implications for Drug Development - A Workshop

Completed

This National Academies public workshop, which was co-hosted by the Forum on Drug Discovery, Development and Translation, and the Forum on Neuroscience and Nervous System Disorders, provided a venue for professionals who typically diagnose ADHD, drug developers, researchers, people with lived experience, and other stakeholders to discuss the diagnosis and treatment of adults with ADHD, explore challenges and opportunities for drug development, and consider strategies for assessing the risks and benefits of ADHD medication treatment in adult populations. The workshop was supported, in part, through a grant (PAR-23-072) from the Center for Drug Evaluation and Research at the FDA.

Description

A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize a public workshop that will provide an opportunity for professionals who typically diagnose attention-deficit/hyperactivity disorder (ADHD) (e.g., physicians, psychologists, social workers, nurse practitioners, and other licensed counselors or therapists), drug developers, researchers, regulators, patients, and other stakeholders to examine the diagnosis and treatment of adults with ADHD and explore the challenges and opportunities for the development of new therapeutics.
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The public workshop will feature invited presentations and discussions to:

  • Discuss the criteria for diagnosis and treatment of adults with ADHD, taking into consideration health disparities and perspectives of people with lived experience.
  • Consider what is known and unknown about the risks and benefits of ADHD medication use in adult populations.
  • Share perspectives on the causes, perceptions, consequences, and health equity implications of non-medical use of prescription stimulants, including misuse potential, overdosage, and toxicity.
  • Explore challenges and opportunities for the development of new and improved therapeutics for the treatment of ADHD.
  • Consider potential strategies for assessing the risks and benefits of ADHD medication treatment in adult populations, including the intersection with opioid use, that support the public health goal of safely and effectively treating adults with ADHD.

The planning committee will organize the workshop, develop the agenda, select and invite speakers and discussants, and moderate or identify moderators for the discussions. A proceedings of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Committee

Co-Chair

Co-Chair

Member

Member

Member

Member

Member

Member

Member

Member

Member

Member

Sponsors

Acadia Pharmaceuticals

Alzheimer's Association

American Brain Coalition

American Neurological Association

Amgen Inc

Association of American Medical Colleges

AstraZeneca

Biogen

Boehringer Ingelheim

Burroughs Wellcome Fund

Cerevel Therapeutics

Cohen Veterans Bioscience

Critical Path Institute

Department of Veterans Affairs

Eisai

Eli Lilly and Company

FasterCures, Milken Institute

Foundation for the National Institutes of Health

Friends of Cancer Research

Gatsby Charitable Foundation

Harmony Biosciences

Janssen Research & Development, LLC

Johnson & Johnson

Karuna Therapeutics

Lundbeck Research USA, Inc.

Medable

Merck & Co., Inc.

Michael J. Fox Foundation for Parkinson's Research

National Cancer Institute

National Center for Advancing Translational Sciences

National Center for Complementary and Integrative Health

National Eye Institute

National Institute of Allergy and Infectious Diseases

National Institute of Environmental Health Sciences

National Institute of Mental Health

National Institute of Neurological Disorders and Stroke

National Institute on Aging

National Institute on Alcohol Abuse and Alcoholism

National Institutes of Health BRAIN Initiative

National Multiple Sclerosis Society

National Science Foundation

New England Journal of Medicine

Office of the Director (National Institutes of Health)

One Mind

Paul G. Allen Frontiers Group

Sanofi

Simons Foundation

Takeda

The George & Anne Ryan Institute for Neuroscience at the University of Rhode Island

U.S. Food and Drug Administration

Wellcome Trust

Staff

Carolyn Shore

Lead

Sheena Posey Norris

Lead

Noah Ontjes

Kelsey Babik

Melvin Joppy

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