A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize and convene a virtual, public workshop focused on the science of engaging youth lived experience in health research, practice, and policy. It will highlight best practices and innovative strategies for engaging youth in research around their well-being, and in the development and implementation of programs and practices aimed at supporting youth well-being. It will also highlight evidence around the impact of youth engagement on science and on youth, including improvements in quality of research and in youth well-being outcomes. The workshop will consider community contexts and policies that may support effective strategies. The workshop will feature lived experience perspectives and other expert presentations. The planning committee will develop the agenda, identify meeting objectives, and select appropriate speakers. A proceedings-in-brief will be prepared by a staff member in accordance with institutional guidelines.