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The Role of Agricultural Practices on Development of Antimicrobial Resistant Microbes Affecting Human Health: A Workshop Series

Completed

Antimicrobial use in agriculture has become a globally widespread practice, while the impact of antimicrobial resistance (AMR) on human, animal, and ecosystem health has become one of the most pressing global health threats. In particular, the use of fungicides in crop production is an area of great concern. This public workshop will explore the role of agricultural practices in AMR development and the implications for human health, with a focus on plant crop production, and consider potential mitigation strategies.

This workshop is funded by U.S. federal government agencies, private for-profit companies, and independent non-profit organizations.

Description

A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize and conduct a public workshop series to shed light on 1) the magnitude of environmentally induced/selected antimicrobial resistance (AMR) in agricultural practices worldwide, with a focus on plant crop production; 2) the practices that contribute to AMR in human pathogens, 3) surveillance strategies, and 4) mitigation strategies.

Three public workshops in this series will feature invited presentations and discussions to explore the following questions:

  • What is the magnitude of antifungal use in crop production in high-, middle- and low-income countries? How are such uses regulated?
  • What are the mechanisms of AMR in plant pathogens and non-target environmental microbiota? How might this influence AMR in human pathogens?
  • Which practices promote, prevent, or reduce the development of AMR in plant production environments, specifically in fungal pathogens? How does this affect risk of produce contamination with AMR pathogens?
  • Are sampling and testing technologies for AMR surveillance in plant production systems worldwide adequate to inform the use of antimicrobials? What further evidence might be needed to inform the use of antimicrobials worldwide? What further evidence is needed to understand the presence and effects of environmental AMR on human health?

The planning committee will organize the workshops, develop the agendas, select and invite speakers and discussants, and moderate or identify moderators for the discussions. One proceedings publication that reports on the presentations and discussions held during this workshop series will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Committee

Co-Chair

Co-Chair

Member

Member

Member

Member

Member

Member

Member

Member

Julie Liao

Staff Officer

Sponsors

American Society of Tropical Medicine and Hygiene

Biomedical Advanced Research and Development Authority (BARDA)

Burroughs Wellcome Fund

Centers for Disease Control and Prevention (CDC)

Department of Health and Human Services

Department of Veterans Affairs

EcoHealth Alliance

ExxonMobil

Infectious Diseases Society of America

Johnson & Johnson

Merck & Co., Inc.

National Institute of Allergy and Infectious Diseases

National Institutes of Health

New Venture Fund

Other, Federal

Private: For Profit

Private: Non Profit

Sanofi

U.S. Food and Drug Administration

Uniformed Services University of the Health Sciences

USAID

Staff

Julie Liao

Lead

Liz Ashby

Claire Biffl

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