In response to Section 5105 of the 2021 National Defense Authorization Act, an ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will study the “current and future impact of artificial intelligence on the workforce of the United States across sectors.” The study will build on and update the 2017 National Academies’ study Information Technology and the U.S. Workforce: Where Are We and Where Do We Go from Here? and consider other recent studies, results from related research programs such as the National Science Foundation’s Future of Work at the Human-Technology Frontier, and other research insights. The committee’s report will review current knowledge about the workforce implications of artificial intelligence and related technologies (including for economic productivity and growth, job stability, equity, and income inequality), identify key open questions, and describe salient research opportunities and data needs. It will not provide recommendations.