An ad hoc committee under the auspices of the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine shall be convened to evaluate the available evidence of the health effects related to the use of electronic nicotine delivery systems (ENDS) and identify future federally funded research needs. As part of its work, the committee will conduct a comprehensive and systematic assessment and review of the literature. The literature review shall include analysis of data on both short and long-term health effects in:
--users of ENDS, including health effects associated with the use of the full range of these devices (e.g., "cig-a-likes," tank systems, mods);
--vulnerable populations of users (e.g., youth, pregnant women, individuals with underlying medical conditions (e.g., heart disease, pulmonary disease));
--nonusers of ENDS exposed to secondhand and thirdhand aerosol generated by use of these devices.

The committee's report will document the findings and provide a list of recommendations for future research. The list of research needs to inform FDA and ENDS regulation will be prioritized with respect to:
--research to gather information of most importance for the regulation of ENDS to protect the population health;
--research that should be a priority for federal funding.