Board on Health Sciences Policy

Meeting Closed

Toward Sequencing and Mapping of RNA Modifications: Committee Meeting 9

July 6, 2023

12:00 PM - 3:00 PM (ET)

Past

About

This is the ninth committee meeting of a consensus study tasked with conducting a study on direct sequencing of modifications of RNA (referred to as epitranscriptome) from humans and model organisms.

This meeting will be held over Zoom.

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Brenda Bass, Markus Hafner, Pat Limbach, Nick Adams, Mary Majumder, Sarath Janga, Taekjip Ha, Keith Nykamp, Jeff Baker, Julius Lucks, Nicole Martinez, Tao Pan

The following topics were discussed in the closed sessions:

During this closed session, the committee debriefed on the recent workforce information session and discussed findings, conclusions, and recommendations for the consensus study.

Organizing Project

Toward Sequencing and Mapping of RNA Modifications

Contact

Steven Moss

(202) 334-3032
smoss@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Workshop

Toward a Common Research Agenda in Infection - Associated Chronic Illnesses: A Workshop to Examine Common, Overlapping Clinical and Biological Factors

June 29 - 30, 2023

Past

Materials

About

Background:

The current concern for “long COVID” underscores an increasing recognition of chronic illnesses that appear to arise from infectious diseases. This overlooked, growing public health problem often includes a patient history of infection by viral or bacterial pathogens followed by long-lasting and often debilitating symptoms including severe fatigue, cognitive impairment, and multi-organ dysfunction. Examples of infection-associated chronic illnesses include:

Long COVID or post-acute sequelae of COVID-19: Between 10 to 30% of patients infected with SARS-CoV-2 develop chronic symptoms that lead to a diagnosis of long COVID. This estimation translates to a disease burden of between 7.7 million and 23 million patients who will be living with long COVID by February 2022.
Myalgic encephalomyelitis/chronic fatigue disease (ME/CFS): ME/CFS onset is often associated with a prior, unidentified infectious episode. Approximately 1.7 to 3.3 million patients in the U.S. are diagnosed with ME/CFS and experience chronic, multi-organ symptoms.
Persistent or post-treatment Lyme disease: Between 10-20% of Lyme disease patients develop persistent and debilitating symptoms after standard antibiotic treatment There are approximately 2 million patients in the U.S. living with persistent or post-treatment Lyme disease syndrome.
Multiple sclerosis: A strong association of multiple sclerosis with Epstein-Barr virus infection was recently reported. In the US, more than 700,000 patients are living with multiple sclerosis.

In addition to the debilitating physical impact on patients, chronic illnesses present broader societal impacts. For example, between 31-70% of COVID patients remain absent from work after the acute phase of the disease and long COVID may be responsible for 1.6 million fewer full-time workers in the U.S. labor market. In the United Kingdom, an estimated economic loss of 32.2 billion pounds over 10 years will be attributable to permanent injury from COVID-19 in adults, 92% of which may be due to long COVID.

Given the commonality in chronic symptoms among long COVID, persistent Lyme disease syndrome, ME/CFS, multiple sclerosis and other conditions, it is not surprising to find similarities in the leading hypotheses for the explanation of these illnesses; e.g., pathogen or antigen persistence, immune response dysregulation, altered neurologic function, and altered microbiome composition and activity. Researchers studying different infection-associated chronic illnesses face common challenges in identifying disease biomarkers and developing diagnostics and therapeutic options.

In addition to this workshop, other National Academies activities are addressing the significance of infection-associated chronic illnesses. The following activities are focused on the impacts of the COVID-19 pandemic:

About:

Participants can attend the workshop both in person and virtually. On June 29 and 30, the Workshop will take place in Keck 100. For those who attend the Workshop in person, breakfast and lunch will be provided.

Planning Committee:

Timothy Coetzee, co-Chair
National Multiple Sclerosis Society

Timothy Endy, co-Chair
CEPI; State University of New York, Upstate Medical University

Amy Proal
PolyBio Research Foundation

Avindra Nath
National Institute of Neurological Disorders and Stroke, NIH

Brian Fallon
Columbia University Irving Medical Center, New York State Psychiatric Institute

Lorraine Johnson
LymeDisease.org, MyLymeData

Melissa Nolan
University of South Carolina

Rafael Obregon
UNICEF

Peter Rowe
Johns Hopkins University School of Medicine, Children's Center

Organizing Project

Toward a Common Research Agenda in Infection-Associated Chronic Illnesses: A Workshop to Examine Common, Overlapping Clinical and Biological Factors

Contact

Claire Biffl

(202) 334-2178
microbialthreats@nas.edu

Location

Keck Center

500 5th St NW

Washington DC 20001, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Roundtable on Mentorship, Well-Being, and Professional Development Meeting #4

June 26, 2023

2:00 PM - 4:00 PM (ET)

Past

About

This is the fourth Roundtable meeting. The Roundtable will explore the on-going improvements and innovations in effective mentorship and professional development practices and programs and how to create and maintain an inclusive and equitable higher education and STEMM research ecosystem.

Organizing Project

Roundtable on Mentorship, Well-Being, and Professional Development

Contact

Maria Lund Dahlberg

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Meeting

Toward Sequencing and Mapping of RNA Modifications: Meeting of Experts on Education and Workforce Development

June 21, 2023

2:30 PM - 4:30 PM (ET)

Past

Agenda

Download the Agenda

About

This meeting of experts will be an opportunity for the committee members to have a discussion with workforce and education development experts as well as current trainees in the RNA Biology field whose research has focused on RNA chemical modifications. During this session we will discuss the workforce needs to support sequencing and analysis of RNA modifications. This will include getting a better understanding of the education and training needs for trainees at various levels. This will also be an opportunity to think about the benefits recruiting a diverse workforce would have in this area of research. The goals of the meeting are to:

Understand the workforce needs to support sequencing and analysis of RNA modifications. What education is required during each level of training (e.g., HS, undergrad, grad, post doc) to establish the proper workforce?
Discuss how a diverse workforce can be recruited into the field of RNA Biology with capacities related to analyzing and understanding RNA chemical modifications. Examine the benefits of cultivating and maintaining a diverse workforce.

Additional Information

Is it a Closed Session event?

Not Closed

Organizing Project

Toward Sequencing and Mapping of RNA Modifications

Contact

Kathryn Asalone

(202) 334-3032
kasalone@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Webinar

Advancing Health and Resilience in the Gulf of Mexico Region: A Roadmap to Progress: Report Release Webinar

June 21, 2023

11:00 AM - 12:00 PM (ET)

Past

About

The Committee on Progress Toward Human Health and Community Resilience in the Gulf of Mexico Region will hold a public webinar to discuss its new report, “Advancing Health and Community Resilience in the Gulf of Mexico Region, A Roadmap for Progress.” The report explores key challenges and priorities in Gulf states (including Alabama, Florida, Louisiana, Mississippi, and Texas) related to human health and community resilience, evaluates progress that has been made in recent years, and presents opportunities for future improvement. Additionally, it makes recommendations for overcoming major challenges, closing critical gaps, and implementing innovative or transformative approaches that focus on the diverse needs and experiences of people who live and work in the Gulf region.

Additional Information

Is it a Closed Session event?

Not Closed

Organizing Project

A Report Series on Progress Toward Human Health and Community Resilience in the Gulf of Mexico Region

Contact

Scott Wollek

(202) 334-1562
SWollek@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Meeting

Developing a Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons Committee Meeting #3

June 15 - 16, 2023

Past

Materials

About

On June 15th, the Committee on Developing a Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons will hold their third committee meeting.

Additional Information

Is it a Closed Session event?

Partially Closed

The following committee members were present at the closed sessions of the event

All committee members were present.

The following topics were discussed in the closed sessions:

Members of the Committee on Developing Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons held a hybrid meeting on June 15 and 16 involving both open and closed sessions. Following the completion of the open session on June 15, committee members met in closed session and deliberated on evidence gathered by and presented to the committee. One June 16, committee members met in closed session to receive briefings on the development of papers commissioned by the committee. The committee members ended the two-day event by considering recommendations and outlining the next steps for the study and report.

The following materials (written documents) were made available to the committee in the closed sessions:

- Agenda
- Briefing Book
- Commissioned Papers

Date of posting of Closed Session Summary:

June 28, 2023

Organizing Project

Developing a Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons

Contact

Study Staff

PRGLACstudy@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Workshop

Toward Sequencing and Mapping of RNA Modifications: Ideation Challenge

June 12 - 13, 2023

Past

Agenda

Download the Agenda

About

This will be a 2 day hybrid event where participants will split into interdisciplinary teams, discuss a challenge in the field of RNA chemical modifications they would like to approach, and come up with innovative ways to approach that challenge.

Additional Information

Is it a Closed Session event?

Not Closed

Organizing Project

Toward Sequencing and Mapping of RNA Modifications

Contact

Steven Moss

(202) 334-3032
smoss@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine: Teleconference June 9

June 9, 2023

1:00 PM - 2:00 PM (ET)

Past

About

This will be a virtual discussion among the committee developing a cross-sectoral governance framework for emerging science, technology, and innovation in health and medicine. It will be closed in its entirety.

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Keith Wailoo
Keith Yamamoto
David Asch
Olveen Carrasquillo
Tony Hatch
Jianying Hu
Lisa Iezzoni
Alex London
Debra Mathews
Shobita Parthasarathy

The following topics were discussed in the closed sessions:

The committee discussed final comments on its draft report in response to feedback from external review.

The following materials (written documents) were made available to the committee in the closed sessions:

Draft report

Date of posting of Closed Session Summary:

June 26, 2023

Organizing Project

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine

Contact

Michael Berrios

MBerrios@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Meeting Closed

Examining the Working Definition for Long COVID - Committee Meeting 4

June 2, 2023

12:00 PM - 3:00 PM (ET)

Past

About

The fourth meeting of the Committee on Examining the Working Definition for Long COVID will be held entirely in closed, committee-only, session.

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

• Harvey Fineberg (Chair)
• Kevin Alexander
• Karyn Bishof
• Lily Chu
• Betty Diamond
• Abigail Dumes
• Wes Ely
• Jerry Krishnan
• Dennis Kolson
• Peter Palese
• Caitlin Pedati
• Mark Smolinski
• Linda Sprague-Martinez
• Andrea Troxel
• Monica Verduzco-Gutierrez

The following topics were discussed in the closed sessions:

• Examine near-final results of stakeholder engagement activities, including questionnaire and focus groups
• Discuss progress on the planning for the June 22-23 Symposium on Long COVID
• Discuss the proposed evidence review approach and methods
• Re-visit the timeline and work plan
• Identify information needs, outstanding issues for full committee consideration, future meeting plans and topics, and next steps

The following materials (written documents) were made available to the committee in the closed sessions:

• Final Agenda
• Draft June 22-23 Symposium Agenda
• Updated Rapid Review Research Plan
• Long COVID Rapid Review Search Strategy
• Summary documents from the initial abstract screening

Date of posting of Closed Session Summary:

June 09, 2023

Organizing Project

Examining the Working Definition for Long COVID

Contact

LongCovid@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Meeting Closed

Toward Sequencing and Mapping of RNA Modifications: Committee Meeting 8

June 1, 2023

1:00 PM - 3:00 PM (ET)

Past

About

This is the eighth committee meeting of a consensus study tasked with conducting a study on direct sequencing of modifications of RNA (referred to as epitranscriptome) from humans and model organisms.

This meeting will be held over Zoom.

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Brenda Bass, TJ Ha, Juan Alfonzo, Kate Meyer, Tao Pan, Nick Adams, Sarath Janga, Mary Majumder, Jeff Baker, Markus Hafner, Susan Baserga

The following topics were discussed in the closed sessions:

During the closed session, the committee reviewed the recent information-gathering session and engaged in a discussion on stakeholder engagement.

Organizing Project

Toward Sequencing and Mapping of RNA Modifications

Contact

Steven Moss

(202) 334-3032
smoss@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine: Teleconference May 26

May 26, 2023

12:00 PM - 1:30 PM (ET)

Past

About

This will be a virtual discussion among the committee developing a cross-sectoral governance framework for emerging science, technology, and innovation in health and medicine. It will be closed in its entirety.

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Keith Wailoo
Keith Yamamoto
Jianying Hu
Alex London
Debra Mathews
Shobita Parthsarathy
Timothy Persons

The following topics were discussed in the closed sessions:

The committee discussed feedback on its draft report from external reviewers.

The following materials (written documents) were made available to the committee in the closed sessions:

Draft report and comments

Date of posting of Closed Session Summary:

June 26, 2023

Organizing Project

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine

Contact

Michael Berrios

MBerrios@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Log In

Sign in to access your saved publications, downloads, and email preferences.

Former MyNAP users: You'll need to reset your password on your first login to MyAcademies. Click "Forgot password" below to receive a reset link via email. Having trouble? Visit our FAQ page to contact support.

Members of the National Academy of Sciences, National Academy of Engineering, or National Academy of Medicine should log in through their respective Academy portals.

Email (required)
Password (required)

Don't have an account?

Register

Email (required)
New password (required)
Retype password (required) Password must be at least 8 characters
I accept the terms of use
terms of use

Thank You

Thank you for creating a MyAcademies account!

Enjoy free access to thousands of National Academies' publications, a 10% discount off every purchase, and build your personal library.

Forgot Password

Enter the email address for your MyAcademies (formerly MyNAP) account to receive password reset instructions.

Reset Requested

We sent password reset instructions to your email . Follow the link in that email to create a new password. Didn't receive it? Check your spam folder or contact us for assistance.

Reset Password

New password (required)
Retype password (required) Password must be at least 8 characters

Reset Password

Your password has been reset.

Log In

Verify email

Verify Your Email Address

We sent a verification link to your email. Please check your inbox (and spam folder) and follow the link to verify your email address. If you did not receive the email, you can request a new verification link below

Subscribe

First Name
Last Name
Email (required)
I agree to receive emails from the National Academies (required)

We respect your privacy and will never share your information.

My Academies

Board on Health Sciences Policy

Toward Sequencing and Mapping of RNA Modifications: Committee Meeting 9

Toward a Common Research Agenda in Infection - Associated Chronic Illnesses: A Workshop to Examine Common, Overlapping Clinical and Biological Factors

Roundtable on Mentorship, Well-Being, and Professional Development Meeting #4

Defining and Evaluating In-Home Drug Disposal Systems for Opioid Analgesics - A Workshop

Symposium on Long COVID: Examining the Working Definition

Toward Sequencing and Mapping of RNA Modifications: Meeting of Experts on Education and Workforce Development

Advancing Health and Resilience in the Gulf of Mexico Region: A Roadmap to Progress: Report Release Webinar

Workshop on Communities, Climate Change, and Health Equity – Lessons Learned in Addressing Inequities in Heat-Related Climate Change Impacts

Developing a Framework to Address Legal, Ethical, Regulatory, and Policy Issues for Research Specific to Pregnant and Lactating Persons Committee Meeting #3

Toward Sequencing and Mapping of RNA Modifications: Ideation Challenge

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine: Teleconference June 9

Next-Generation Screening - The Promise and Perils of DNA Sequencing of Newborns at Birth: A Workshop

Examining the Working Definition for Long COVID - Committee Meeting 4

Toward Sequencing and Mapping of RNA Modifications: Committee Meeting 8

Creating a Framework for Emerging Science, Technology, and Innovation in Health and Medicine: Teleconference May 26