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The Clinical Application of Computational Methods and Big Data in Precision Oncology - A Workshop

Completed

Precision oncology therapies, which target specific abnormalities in a patient’s cancer, are changing the nature of cancer treatment by enabling clinicians to select therapies that are most likely to benefit individual patients. Increasingly, oncologists are formulating cancer treatment plans using results from complex tests that characterize the molecular underpinnings of an individual patient’s cancer. These advances depend on the use of computational methods to analyze large-scale datasets derived from genomic tests and other omics technologies. This workshop examined the challenges and opportunities in the development of computational methods for precision medicine to improve cancer diagnosis and care.

Description

An ad hoc committee will plan and host a 1.5-day public workshop to examine the clinical use of high-dimensional (omics) data and computational methods in precision oncology research and clinical care. The workshop will feature invited presentations and panel discussions on topics that may include:

  • Challenges and opportunities to use omics data to develop precision medicine approaches and technologies in cancer care.
  • Potential standards and best practices for computational software and methodological approaches for the use of big data to inform clinical care of patients with cancer, especially in regard to multi-parameter/multi-treatment testing and interpretation.
  • Potential opportunities to improve the translation of omics technologies into oncology practice, such as harmonization of standards for omics-based discovery, development and evaluation; data sharing and reproducibility; oversight and regulation; education, training, and workforce needs; and the use of dissemination and implementation science strategies.

The committee will develop the agenda for the workshop sessions, select and invite speakers and discussants, and moderate the discussions. A proceedings of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Sponsors

American Association for Cancer Research

American Cancer Society

American College of Radiology

American Society of Clinical Oncology

Association of American Cancer Institutes

Association of Community Cancer Centers

Bristol Myers Squibb

Cancer Support Community

Centers for Disease Control and Prevention (CDC)

CEO Roundtable on Cancer

Flatiron Health

Helsinn Therapeutics (U.S.), Inc.

LiveSTRONG Foundation

Merck

National Cancer Institute

National Comprehensive Cancer Network

National Institutes of Health

Novartis Oncology

Oncology Nursing Society

Pfizer Inc.

Staff

Sharyl Nass

Lead

Erin Balogh

Lead

Cyndi Trang

Emily Zevon

Ruth Cooper

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